Check WoW/Errors folder and if there are files what were created at relatively same time as your crash-to-desktop (CTD) happened, then upload latest .txt file dump on sites like [url="https://mega.nz/"><s></s>https://mega.nz/, then provide a link in your reply.
Addition questions:
Addition questions:
- Where is your WoW located? Some folders on your storage have tighter security settings, what may prevent WoW working correctly. Best place to have WoW at would be at the root of your storage drive (e.g. under C:/).
- What are the contents of your WoW/Data and WoW/Data/enGB? WoW/Data should look like this: [url="http://i.imgur.com/8svu7cf.jpg"><s></s>http://i.imgur.com/8svu7cf.jpg (screenshot doesn't include latest custom patch wow-update-base-18549.MPQ, which should also be there). WoW/Data/enGB should look like this: [url="http://i.imgur.com/AZqtAUH.jpg"><s></s>http://i.imgur.com/AZqtAUH.jpg
- Have you tried deleting both caches (WoW/Cache and WoW/Data/Cache)?